The odds are stacked against Senate Democrats this fall, as they try to hang onto their razor-thin majority in November. Not only will they have to defend 22 incumbent seats, many in Republican-leaning states, but they will also have to offset the loss of West Virginia Senator Joe Manchin, who announced his retirement from the Senate last year.

West Virginia is one of the reddest states in the nation and Democrats don’t see a path to retain the seat without Manchin. Their best but unlikely hope is to pick up a seat in either Texas or Florida, where Sen. Ted Cruz and Sen. Rick Scott are running for reelection.

There are currently 48 Democrats, plus three independents who caucus with them, giving them a 51-49 majority. Here’s where the Senate map stands nine months from Election Day and a look at the earliest fundraising numbers for the year.